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KMID : 0363320210420010053
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Journal of Korean Oriental Internal Medicine
2021 Volume.42 No. 1 p.53 ~ p.66
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Review on Herbal Medicine Treatment for Late Complications of COVID-19 Patients
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Lee Kyoung-Eun
Jeong Seon-Hyung
Jeong Min-Jeong
Choi Yoo-Min
Song Mi-Deok
Jang In-Soo
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Abstract
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Objective: The purpose of this study was to collect and evaluate evidence of herbal medicine treatments for the residual effects of COVID-19.
Methods: Nine electronic databases, namely PubMed, Science Direct, CINAHL, CNKI, Wanfang, J-STAGE, CiNii, OASIS, and Science ON, were searched with the following keywords: ‘COVID-19’; ‘sequelae’; ‘Convalescence’ for ‘P (Population)’ and ‘Medicine, Chinese Traditional’; ‘Korean medicine’; ‘Herbal medicine’ for ‘I (Intervention)’. For the selected studies, various clinical data were extracted including patient symptoms, pattern identification, herbal medicines prescribed, and treatment results.
Results: A total of nine clinical studies were identified (two case control trials; one case series; and six case reports). Various residual symptoms had been detected in the recovery stage of COVID-19 with the most commonly used pattern identifications being deficiency in both lung and spleen and in both qi and yin. Any herbal medicine prescriptions were written using these patterns. We found several reports of the positive effect of herbal medicines in that it improved symptoms, lung function, and lung inflammation. No adverse events were reported.
Conclusions: The results indicate that treatment with herbal medicines has a possible therapeutic effect on the residual symptoms of COVID-19. Large-scale studies are necessary to confirm the effectiveness of these approaches.
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KEYWORD
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COVID-19, sequelae, convalescence, herbal medicine, Korean medicine, traditional Chinese medicine
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